Friday, 20 February 2015

MNEMONICS TO REMEMBER MICROSOMAL ENZYME INDUCERS , ENZYME INHIBITORS , etc .

                                   MNEMONICS 


MENTION SOME ENZYME INDUCERS ????
MENTION SOME ENZYME INHIBITORS ????
MENTION DRUGS METABOLIZED BY MICROSOMAL ENZYMES ????
MENTION DRUGS METABOLIZED BY ACETYLATION ????

These above questions are frequently asked in MBBS viva exam and for PG entrance too . So I gathered some mnemonics to answers these questions easily . I wanted to share this so that it will be helpful for others too . 

ENZYME INDUCERS :

                                GPRS Cell Phone

G - Griseofulvin 
P - Phenytoin
R - Rifampicin 
S - Smoking
Cell - Carbamazepine 
Phone - Phenobarbitone 

ENZYME INHIBITORS :

                           Vitamin K Cannot Cause Enzyme Inhibition 

Vitamin - Valproate 
K - Ketoconazole 
Cannot - Cimetidine 
Cause - Ciprofloxacin 
Enzyme - Erythromycin 
Inhibition - Isoniazid

DRUGS METABOLIZED BY MICROSOMAL ENZYMES :

                     COW PATS

C - Cyclosporin
O - Oral Contraceptive Pills 
W - Warfarin 
P - Phenytoin
A - Acetyl choline esterase inhibitor ( DONEZEPIL )   
T - Theophylline 
S - Statins

DRUGS METABOLIZED BY ACETYLATION :

                              D SHIP

D - Dapsone 
S - Sulphonamide 
H - Hydralazine 
I - Isoniazid 
P - Procainamide 





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